Table IV.

Association between protein S100-A8 expression levels and the clinicopathological characteristics of 192 patients with breast cancer.

		S100-A8 protein expression
Characteristic	N	No	Yes	P-value
Age at diagnosis, years
<50	114	76	38	0.363
≥50	78	47	31
Histological type
Ductal	156	94	62	0.022a
Lobular	36	29	7
Histological grade
I–II	35	20	15	0.345
III	157	103	54
Nodal status
Negative	83	52	31	0.722
Positive	109	71	38
Tumor size, cm
≤2	58	40	18	0.630
2–5	111	69	42
>5	20	12	8
Unknown	3
Clinical stage
I	29	20	9	0.313
II	98	66	32
III	62	35	27
Unknown	3
ER
Negative	90	49	41	0.009a
Positive	102	74	28
PR
Negative	78	48	30	0.547
Positive	114	75	39
Cerb B-2
Negative	58	42	16	0.118
Positive	124	75	39
Unknown	10
Menstrual history
Premenopause	126	84	42	0.299
Postmenopause	66	39	27

^aP<0.05, according to χ² test. Unknown cases are excluded from p-value calculations. ER, estrogen receptor expression; PR, progesterone receptor expression.