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. 2018 Feb 13;15(4):5593–5601. doi: 10.3892/ol.2018.8032

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Copyright: © Luo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Treatment with curcumin significantly increases the mRNA levels of CLTC and ITPR1 and decreases the mRNA levels of ADAM15 in curcumin-treated cells compared with dimethyl sulfoxide-treated and control cells, *P<0.01 compared with control cells, ^#P<0.01 compared with dimethyl sulfoxide-treated cells. EEF1A1, eukaryotic translation elongation factor 1α1; ATF7IP, activating transcription factor 7 interacting protein; HIF1A, hypoxia-inducible factor-1α; SMAD7, SMAD family member 7; CLTC, clathrin heavy chain; MCM10, minichromosome maintenance 10 replication initiation factor; ITPR1, inositol 1,4,5-triphosphate receptor type 1; ADAM15, a disintegrin and metalloprotease 15; WWP2, WW domain containing E3 ubiquitin protein ligase 2; ATP5C1, ATP synthase, H⁺ transporting, mitochondrial F1 complex, gamma polypeptide 1; Con, control; DMSO, dimethyl sulfoxide.