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. 2018 Feb 13;15(4):5977–5982. doi: 10.3892/ol.2018.8038

Figure 3.

Figure 3.

Restored miR-139 expression inhibits gastric cancer cell proliferation, migration and invasion by regulation of ROCK1. (A) miR-139 expression in BGC-823 and SGC-7901 cells transfected with miR-139 mimics or NC was detected at 48 h post-transfection. (B) The proliferative ability of BGC-823 and SGC-7901 cells co-transfected with NC, miR-139 mimic or miR-139 mimic + pcDNA3.1-ROCK1 was determined. (C) Cell migration and (D) invasion assays of BGC-823 and SGC-7901 cells transfected with NC, miR-139 mimic or miR-139 mimic + pcDNA3.1-ROCK1. (E) ROCK1 mRNA expression in BGC-823 and SGC-7901 cells transfected with pcDNA3.1-ROCK1 or pcDNA3.1-Control. *P<0.05 vs. control. miR-139, microRNA-139; ROCK1, ρ-associated protein kinase 1; NC, negative control.