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. 2018 Feb 7;15(4):4821–4826. doi: 10.3892/ol.2018.7988

Figure 3.

Figure 3.

Curcumin inhibits VEGF protein expression and PI3K/AKT signaling in vivo. (A) Immunohistochemistry images of VEGF protein expression levels in the control group and the 50 and 100 mg/kg curcumin-treated groups. (B) Representative western blot images and quantification of VEGF and PI3K/AKT protein expression levels in the control group and the 50 and 100 mg/kg curcumin-treated groups. β-actin served as an internal control. #P<0.05 and ##P<0.01 compared with control. VEGF, vascular endothelial growth factor; PI3K, phosphoinositide 3-kinase; AKT, AKT serine/threonine kinase 1.