Fig. 7.
Exogenous TIPE3 with C-terminal flag promotes tumor growth in vivo. A549 cells (3 × 106 cells in 100 μl PBS per mice) transfected with mock or recombinant (carrying C-terminal flag-tagged human TIPE3) lentivirus were subcutaneously injected into nu/nu mice (n = 5 per group) to establish xenograft tumors. a-d The growth curve of tumors (a), tumor size (b, c) and weight (d) were determined. e TIPE3 expression was evaluated in sections of tumor tissues by immunohistochemistry. *P < 0.05, ***P < 0.001