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. 2018 Mar 6;19:183. doi: 10.1186/s12864-018-4507-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — JAK/STAT3 Controls the Expression of Key Histone Modifiers. a Heatmap of FPKM value comparison for Dnmt, Hdac, and Hat/Kat genes detected under two different treatments and reprogramming stages. The relative abundance is represented by color (blue, lower abundance; red, higher abundance), as indicated by the color key. b Heatmap of FPKM value comparison for PRC2 component genes detected under two different treatments and reprogramming stages. The relative abundance is represented by color (blue, lower abundance; red, higher abundance), as indicated by the color key. c qPCR analysis of PRC2 component gene expressions in two different reprogramming conditions and stages. R1-ESC was used as the control. Bars represent mean ± SD from three independent experiments. **: p < 0.01