Table 2.
Fold change of HLA expression induced by IFN-α and IFN-γ in each cell type analyzed
| Fold change HLA-E (IFN-α) | Fold change HLA-E (IFN-γ) | Fold change HLA-ABC (IFN-α) | Fold change HLA-ABC (IFN-γ) | Fold change HLA-DR (IFN-α) | Fold change HLA-DR (IFN-γ) | |
|---|---|---|---|---|---|---|
| B cells | 1.733 | 1.503 | 1.286 | 1.202 | 0.979 | 1.041 |
| CD4 T cells | 1.790 | 1.514 | 1.554 | 1.267 | 0.921 | 1.070 |
| CD8 T cells | 1.609 | 1.343 | 1.510 | 1.207 | 0.976 | 1.098 |
| NK cells | 2.124 | 1.487 | 1.739 | 1.292 | 1.558 | 1.750 |
| Monocytes | 2.261 | 1.377 | 2.096 | 1.539 | 1.458 | 3.131 |
Mean values of fold change in HLA-E, HLA-ABC, and HLA-DR expression in different cell types of both MS patients (n = 14) and controls (n = 11) after 24 h of IFN-α and IFN-γ stimulation