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. 2018 Feb 7;15(4):3231–3238. doi: 10.3892/etm.2018.5843

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Thymosin α1 treatment inhibits hepatocyte apoptosis in D-galactosamine hydrochloride/lipopolysaccharide-induced ALF. Liver tissues were harvested at 3, 6, 9 and 12 h after the establishment of a rat model of ALF and a TUNEL assay was performed (magnification, ×400). Representative images from 3 rats/group were selected. (A) MG at a-1, 3 h; a-2, 6 h; a-3, 9 h; and a-4, 12 h. (B) TG at b-1, 3 h; b-2, 6 h; b-3, 9 h; and b-4, 12 h. (C) CG 3 h. (D) Quantification of liver cell apoptosis. Data are expressed as the mean ± standard error of the mean (n=3). *P<0.05 vs. the CG group. ALF, acute liver failure; CG, control group; MG, model group; TG, treatment group; AI, apoptotic index.