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. 2018 Feb 12;15(4):3530–3536. doi: 10.3892/etm.2018.5858

Figure 1.

Figure 1.

Berberine significantly reduces inflammatory cytokine levels in the peripheral blood of mice with neonatal NEC. Mice with neonatal NEC were treated with either berberine or PBS (as a control) and levels of (A) TLR-4, (B) MD-2, (C) TNF-α, (D) NF-κB, (E) IL-6 and (F) Cxcl-1 in the peripheral blood was determined by ELISA. **P<0.01. NEC, necrotizing enterocolitis; TLR, toll like receptor; MD, myeloid differentiation protein; TNF, tumor necrosis factor; NF nuclear factor; IL, interleukin; Cxcl, (C-X-C motif) ligand.