Table IV.
Comparison of serum adipokine levels between the study groups.
Analyte | Control (n=19) | CD (n=11) | UC (n=23) | P-value |
---|---|---|---|---|
C peptide (pg/ml) | 975.4±281.0 | 1,112.6±468.2 | 905.19±528.5 | 0.208 |
Ghrelin (pg/ml) | 3,471.4±878.9 | 4,192.5±1,929.8 | 3,584.94±1,245.1 | 0.745 |
GIP (pg/ml) | 426.4±197.6 | 635.3±506.2 | 469.7±301.1 | 0.150 |
GLP-1 (pg/ml) | 817.5±46.7 | 860.4±133.0 | 822.71±125.0 | 0.292 |
Glucagon (pg/ml) | 1,119.4±64.9 | 1,184.7±163.7 | 1,141.4±91.5 | 0.251 |
Insulin (pg/ml) | 911.8±236.1 | 1,052.0±291.4 | 918.68±310.5 | 0.176 |
Leptin (pg/ml) | 8,847.6±4,044.22 | 7,257.4±8,051.3 | 3,978.26±2,787.0 | 0.001a |
PAI-1 (pg/ml) | 82,870.7±38,624.1 | 109,456.2±93,303.5 | 64,411±23,996.3 | 0.090 |
Resistin (pg/ml) | 5,131.0±3,061.5 | 5,189.8±2,282.6 | 41,58.01±1,782.3 | 0.457 |
Visfatin (pg/ml) | 4,494.1±883.2 | 6,230.6±6,232.3 | 14,201.0±44,005 | 0.745 |
P<0.05 Control vs. UC vs. CD (analysis of variance test). Serum levels of the proteins were determined at baseline. Values are expressed as the mean ± standard deviation. IBD, inflammatory bowel disease; GIP, gastric inhibitory polypeptide; GLP, glucagon-like peptide-1; PAI-1, total plasminogen activator inhibitor-1; UC, ulcerative colitis; CD, Crohn's disease.