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. 2018 Feb 12;15(4):3345–3351. doi: 10.3892/etm.2018.5856

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Copyright: © Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Sensitivity of non-small cell lung cancer cell lines to TNF-α treatment. (A) H292, (B) H1975, (C) H460, and (D) H1299 cell lines were treated with 20, 40, or 80 ng/ml TNF-α and cell viability was assessed. The cell viability was normalized to the control group at 0 h. An increased level of cleaved caspase-3 was observed in (E) H460 and (F) H1299 cells following TNF-α treatment. *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001 vs. Ctrl. Ctrl, control; NSCLC, non-small cell lung cancer; TNF, tumor necrosis factor; OD, optical density.