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. 2018 Feb 14;15(4):3603–3608. doi: 10.3892/etm.2018.5867

Figure 5.

Figure 5.

GDF-5 overexpression protects NP cells from LPS-induced matrix degradation. (A) Western blotting results for the protein expression levels of collagen-II and aggrecan. Stimulation of NP cells with LPS significantly reduced (B) collagen-II and (C) aggrecan content. GDF-5 overexpression significantly inhibited the decrease of collagen-II and aggrecan compared with that in the LPS group. **P<0.01 vs. Ctrl group; #P<0.05 vs. LPS group. NP, nucleus pulposus; GDF-5, growth and differentiation factor-5; LPS, lipopolysaccharide; Ctrl, control.