Table 1.
Information about the enhancement phase for different regions of interest within CSF and venous space and brain parenchyma
| Enhancement phase | Baseline (SU) | Max increase (SU) | Time to peak (min) | Enhancement coefficient (SU/min) | ||||
|---|---|---|---|---|---|---|---|---|
| iNPH | REF | iNPH | REF | iNPH | REF | iNPH | REF | |
| CSF space | ||||||||
| Foramen magnum | 10.3 + 3.4 | 8.9 + 2.6 | 398.3 ± 108.0 | 426.0 ± 123.0 | 174.5 ± 94.2 | 129.4 ± 156.7 | 5.9 ± 12.2 | 17.7 ± 24.5 |
| Sylvian fissure | 7.0 + 1.6 | 8.6 + 3.6 | 226.2 ± 100.2 | 204.2 ± 104.4 | 689.0 ± 536.3a | 258.6 ± 114.8 | 0.57 ± 0.41 | 0.9 ± 0.7 |
| Pontine cistern | 10.2 + 3.7 | 9.5 + 1.3 | 378.2 ± 133.0 | 388.5 ± 121.7 | 230.9 ± 98.4 | 159.8 ± 148.9 | 2.4 ± 2.3 | 10.8 ± 18.2 |
| Fourth ventricle | 11.3 + 3.1 | 12.6 + 3.0 | 386.5 ± 138.2a | 236.0 ± 142.9 | 286.7 ± 322.9 | 123.4 ± 98.1 | 5.6 ± 14.5 | 6.3 ± 14.0 |
| Third ventricle | 14.4 + 2.6 | 14.5 + 2.8 | 243.6 ± 136.9a | 115.1 ± 103.8 | 615.3 ± 587.5 | 253.8 ± 133.2 | 1.4 ± 1.7 | 0.4 ± 0.4 |
| Lateral ventricle | 6.0 + 1.2c | 9.4 + 1.5 | 168.5 ± 99.8b | 42.5 ± 51.9 | 843.4 ± 560.2 | 402.6 ± 446.1 | 0.41 ± 0.39 | 0.13 ± 0.16 |
| Precentral sulcus | 7.6 + 1.6 | 8.1 + 1.2 | 131.1 ± 94.1 | 87.8 ± 99.3 | 1254.7 ± 483.8b | 475.0 ± 601.9 | 0.10 ± 0.06 | 0.29 ± 0.39 |
| Central venous space | ||||||||
| Sagittal sinus/confluence | 34.9 + 7.2 | 32.3 + 7.6 | 8.1 ± 8.0 | 7.4 ± 9.6 | 350.2 ± 457.3 | 524.4 ± 591.3 | 0.16 ± 0.25 | 0.41 ± 0.85 |
| Brain parenchyma | ||||||||
| Inferior frontal gyrus | 82.5 + 4.3b | 89.5 + 3.2 | 39.1 ± 25.3 | 23.8 ± 20.9 | 1358.0 ± 313.4 | 1421.3 ± 53.1 | 0.03 ± 0.02 | 0.02 ± 0.02 |
| Pons | 96.8 + 4.2a | 101.1 + 4.8 | 11.6 ± 7.0 | 7.4 ± 5.8 | 1090.0 ± 602.3 | 929.4 ± 676.9 | 0.03 ± 0.08 | 0.08 ± 0.17 |
| Thalamus | 86.7 + 4.8b | 93.9 + 6.0 | 13.0 ± 6.8 | 9.0 ± 7.1 | 1261.7 ± 462.6 | 1288.4 ± 386.3 | 0.01 ± 0.02 | 0.01 ± 0.01 |
| Frontal horn | 63.9 + 18.4b | 94.1 + 15.7 | 48.5 ± 32.8b | 7.9 ± 7.9 | 1349.3 ± 350.9 | 1109.8 ± 585.6 | 0.04 ± 0.02 | 0.05 ± 0.12 |
| Precentral gyrus | 82.7 + 6.0 | 87.4 + 3.7 | 9.0 ± 8.3 | 7.8 ± 11.2 | 900.0 ± 686.4 | 742.8 ± 727.9 | 0.04 ± 0.06 | 0.03 ± 0.03 |
Significant differences between iNPH and REF groups were determined by independent samples t-test: aP < 0.05, bP < 0.01, cP < 0.001.
REF = reference subject; SU = signal unit.