Table 2.

Associations Between Plasma IL-1ra Concentrations and Metabolic Variables

	n	βa	Pb	βc	Pd
BMI SDS	126	0.50	<0.001e,f	n/a	n/a
WHtR	125	0.63	<0.001e,f	n/a	n/a
Δ Weight SDS, 0–2 y	124	0.19	0.047	n/a	n/a
Δ Weight SDS, after 2 y	124	0.23	0.024	n/a	n/a
Cholesterol	126	0.08	0.466	0.14	0.413
HDL-C	126	−0.23	0.022f	−0.12	0.447
LDL-C	126	0.18	0.066f	0.20	0.197
TG	126	0.25	0.018f	0.19	0.181
AI	126	0.28	0.007f	0.19	0.257
ALT	126	0.14	0.167	0.05	0.840
Glucose	125	−0.04	0.678	0.02	0.857
Insulin	126	0.24	0.019f	0.04	0.769
HOMA-IR	125	0.22	0.022f	0.04	0.706
hs-CRP	116	0.51	<0.001e,f	0.43	<0.001
25(OH)D	120	−0.24	0.021	−0.24	0.135
Systolic blood pressure	124	−0.01	0.869	−0.09	0.591
Diastolic blood pressure	124	−0.03	0.433	−0.04	0.516

Abbreviations: n/a, not applicable; Δ Weight SDS, change in weight SDS.

^aGLM adjusted for sex and age.

^bFDR-corrected P values for GLM adjusted for sex and age.

^cGLM adjusted for sex, age, and BMI SDS at examination.

^dFDR-corrected P values for GLM adjusted for sex, age, and BMI SDS at examination.

^eThe association is significant in the LGA group.

^fThe association is significant in the AGA group.