Table 2.
Single treatment | Repeated treatment |
P value (single vs. first repeated) | P value (first vs. second Tx) | ||
---|---|---|---|---|---|
(n = 186) Median (IQR) |
First Tx (n = 111) Median (IQR) |
Second Tx (n = 111) Median (IQR) |
|||
Cell number (×106 mononuclear cells) | 168 (109–254) | 151 (93–240) | 123 (80–200) | 0.20 | 0.07 |
SDF-1-induced migration capacity | 90 (59–146) | 97 (61–142) | 104 (65–155) | 0.72 | 0.61 |
Colony-forming unit capacity | 23 (16–38) | 20 (14–32) | 20 (13–28) | 0.02 | 0.29 |
CD45+CD34+ cells (%) (assay 1a, n = 181) | 2.1 (1.2–2.9) (n = 114) | 1.8 (0.8–2.5) (n = 44) | 2.0 (0.9–3.1) (n = 23) | 0.34 | 0.92 |
CD45+CD34+ cells (%) (assay 2a, n = 220) | 1.3 (1.1–1.8) (n = 65) | 1.3 (1.0–1.8) (n = 67) | 1.4 (1.0–2.0) (n = 88) | 0.99 | 0.90 |
aThe FACS protocol and antibodies were changed during the ongoing registry.