Table 3.
Echocardiographic measures—changes from baseline to 6 months—per protocol population
| RVA (n = 92) |
RVS (n = 90) |
P-value | |||||
|---|---|---|---|---|---|---|---|
| Baseline | 6 Months | Change | Baseline | 6 Months | Change | ||
| LVESV (mL) | |||||||
| Mean ± SD | 153.5 ± 72.3 | 124.2 ± 66.9 | −29.3 ± 44.5 | 157.8 ± 82.5 | 132.5 ± 85.9 | −25.3 ± 39.4 | 0.788 |
| Median | 134.0 | 115.0 | −20.0 | 141.5 | 110.0 | −19.5 | |
| Q1; Q3 | 105.5; 182.5 | 78.0; 154.0 | −47.5; 0.0 | 106.0; 191.0 | 84.0; 163.0 | −50.0; 0.0 | |
| LVESD (mm) | |||||||
| Mean ± SD | 62.0 ± 11 | 58.6 ± 13.4 | −3.4 ± 7.6 | 64.8 ± 11.8 | 61.4 ± 13 | −3.5 ± 7.2 | 0.681 |
| Median | 60.0 | 56.5 | 0.0 | 63.5 | 61.0 | −1.0 | |
| Q1; Q3 | 55.0; 70.0 | 50.0; 70.0 | −6.0; 0.0 | 56.5; 71.0 | 52.0; 69.0 | −6.0; 0.0 | |
| LVEDV (mL) | |||||||
| Mean ± SD | 215.2 ± 84 | 189.7 ± 77.1 | −25.5 ± 47 | 220.6 ± 93.8 | 195.3 ± 95.8 | −25.3 ± 47.7 | 0.959 |
| Median | 198.5 | 178.0 | −19.5 | 209.0 | 177.5 | −18.0 | |
| Q1; Q3 | 159.5; 247.0 | 134.0; 229.0 | −46.5; 0.0 | 156.0; 262.0 | 139.0; 227.0 | −48.0; 0.0 | |
| LVEDD (mm) | |||||||
| Mean ± SD | 72.2 ± 11.3 | 69.3 ± 12.8 | −2.9 ± 6.9 | 74.1 ± 11.4 | 71.6 ± 11.9 | −2.5 ± 7.4 | 0.925 |
| Median | 71.0 | 68.0 | 0.00 | 74.0 | 70.0 | 0.0 | |
| Q1; Q3 | 66.0; 77.0 | 61.0; 77.0 | −8.0; 0.0 | 65.5; 81.0 | 64.0; 78.0 | −5.0; 0.0 | |
| LVEF (%) | |||||||
| Mean ± SD | 30.0 ± 7.7 | 35.9 ± 10.2 | 6.0 ± 8.7 | 29.7 ± 8.2 | 35.5 ± 9.9 | 5.8 ± 9.1 | 0.770 |
| Median | 30.0 | 36.0 | 3.0 | 30.0 | 36.0 | 4.0 | |
| Q1; Q3 | 26.0; 34.0 | 29.0; 42.0 | 0.0; 10.0 | 25.0; 35.0 | 28.0; 41.0 | 0.0; 10.0 | |
| LV filling time (ms) | |||||||
| Mean ± SD | 383.9 ± 122.6 | 431.8 ± 127 | 48 ± 120 | 377.5 ± 155.4 | 431.2 ± 143.8 | 53.8 ± 133.7 | 0.353 |
| Median | 381.0 | 435.0 | 29.0 | 365.5 | 414.0 | 50.0 | |
| Q1; Q3 | 284.0; 452.0 | 341.0; 525.0 | 0.0; 97.0 | 275.5; 440.0 | 324.0; 512.0 | 0.0; 125.5 | |
LVESV, left ventricular end-systolic volume; LVESD, left ventricular end-systolic diameter; LVEDV, left ventricular end-diastolic volume; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction.