Table 4.
Echocardiographic measures—change from baseline to 12 months—per protocol population
| RVA (n = 92) |
RVS (n = 90) |
P-value | |||||
|---|---|---|---|---|---|---|---|
| Baseline | 12 Months | Change | Baseline | 12 Months | Change | ||
| LVESV (mL) | |||||||
| Mean ± SD | 153.5 ± 72.3 | 114.98 ± 67.79 | −38.55 ± 50.92 | 157.8 ± 82.5 | 125.77 ± 88.63 | −32.0 ± 43.21 | 0.472 |
| Median | 134.0 | 104.0 | −32.0 | 141.5 | 105.5 | −24.5 | |
| Q1; Q3 | 105.5; 182.5 | 68.0; 139.5 | −60.5; −2.0 | 106.0; 191.0 | 76.0; 144.0 | −58.0; 0.0 | |
| LVESD (mm) | |||||||
| Mean ± SD | 62.0 ± 11 | 56.70 ± 14.16 | −5.26 ± 8.33 | 64.8 ± 11.8 | 58.72 ± 12.91 | −6.11 ± 8.36 | 0.645 |
| Median | 60.0 | 55.5 | −2.5 | 63.5 | 57.0 | −4.0 | |
| Q1; Q3 | 55.0; 70.0 | 48.0; 67.0 | −10.0; 0.0 | 56.5; 71.0 | 50.0; 67.5 | −11.0; 0.0 | |
| LVEDV (mL) | |||||||
| Mean ± SD | 215.2 ± 84 | 178.08 ± 80.6 | −37.16 ± 55.87 | 220.6 ± 93.8 | 188.01 ± 99.03 | −32.63 ± 53.68 | 0.419 |
| Median | 198.5 | 168.0 | −34.0 | 209.0 | 166.0 | −21.0 | |
| Q1; Q3 | 159.5; 247.0 | 123.0; 211.0 | −62.0; 0.0 | 156.0; 262.0 | 129.0; 215.0 | −64.0; 4.0 | |
| LVEDD (mm) | |||||||
| Mean ± SD | 72.2 ± 11.3 | 68.93 ± 13.27 | −3.28 ± 6.59 | 74.1 ± 11.4 | 69.56 ± 12.34 | −4.55 ± 7.39 | 0.515 |
| Median | 71.0 | 67.0 | −1.0 | 74.0 | 68.0 | −3.0 | |
| Q1; Q3 | 66.0; 77.0 | 60.0; 76.0 | −9.0; 0.0 | 65.5; 81.0 | 60.0; 76.0 | −9.0; 0.0 | |
| LVEF (%) | |||||||
| Mean ± SD | 30.0 ± 7.7 | 38.15 ± 11.44 | 8.21 ± 10.04 | 29.7 ± 8.2 | 36.49 ± 10.32 | 6.78 ± 9.67 | 0.722 |
| Median | 30.0 | 39.0 | 7.0 | 30.0 | 36.5 | 7.5 | |
| Q1; Q3 | 26.0; 34.0 | 30.0; 44.0 | 0.0; 13.5 | 25.0; 35.0 | 30.0; 42.0 | 0.0; 14.0 | |
| LV filling time (ms) | |||||||
| Mean ± SD | 383.9 ± 122.6 | 442.38 ± 130.47 | 58.52 ± 110.94 | 377.5 ± 155.4 | 418.61 ± 124.37 | 41.16 ± 152.75 | 0.966 |
| Median | 381.0 | 433.0 | 39.0 | 365.50 | 416.00 | 55.0 | |
| Q1; Q3 | 284.0; 452.0 | 358.0; 536.0 | −10.0; 122.0 | 275.5; 440.0 | 338.0; 492.0 | −11.5; 129.0 | |
LVESV, left ventricular end-systolic volume; LVESD, left ventricular end-systolic diameter; LVEDV, left ventricular end-diastolic volume; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction.