Table 4.
Associations of two or more stressful life events and gender with transitions in ongoing vs. remitted DSM-5 SUD diagnoses.
| Main effects |
Two-way interaction |
||||
|---|---|---|---|---|---|
| Stress (2+ events vs. 0 or 1
event) |
Gender (female vs.
male) |
Stress by gender |
|||
| OR (95% CI) | Wald χ2 | OR (95% CI) | Wald χ2 | Wald χ2 | |
| Alcohol use disorder | 2.39 (2.14, 2.68) | 231.22a | 0.80 (0.71, 0.90) | 13.13a | ns |
| Tobacco use disorder | 2.62 (2.31, 2.97) | 228.02a | ns | ns | |
| Cannabis use disorder | 2.95 (2.18, 4.01) | 48.48a | ns | ns | |
| Opioid use disorder | ns | ns | ns | ||
Note: DSM-5: Diagnostic and Statistical Manual of Mental Disorders Fifth Edition; SUD: substance use disorder; OR: odds ratio; CI: confidence interval; ns: nonsignificant.
a
All Walds significant at p < 0.001 unless specified with ns.