Table 1.
Statistical analysis of proteins identified mass spectrometry analysis of MID1 immunoprecipitates
| Protein name | Gene ID | Log2 ratio | P-value |
|---|---|---|---|
| ATP-binding cassette sub-family D member 3 | ABCD3 | 2.75E+01 | 2.04E-03 |
| ATP-binding cassette sub-family F member 2 | ABCF2 | 2.88E+01 | 5.96E-04 |
| Apoptotic chromatin condensation inducer in the nucleus | ACIN1 | 2.72E+01 | 1.39E-02 |
| Aldehyde dehydrogenase X, mitochondrial | ALDH1B1 | 2.62E+01 | 3.61E-04 |
| Mitochondrial 10-formyltetrahydrofolate dehydrogenase | ALDH1L2 | 2.66E+01 | 1.97E-02 |
| THO complex subunit 4 | ALYREF | 2.99E+01 | 7.55E-04 |
| Serine/threonine-protein phosphatase 6 reg. ankyrin repeat subunit A | ANKRD28 | 2.63E+01 | 1.85E-02 |
| Coatomer subunit delta | ARCN1 | 2.65E+01 | 2.36E-02 |
| Activating signal cointegrator 1 complex subunit 3 | ASCC3 | 2.59E+01 | 7.96E-03 |
| ATPase family AAA domain-containing protein 3A | ATAD3A | 1.77E+00 | 3.98E-02 |
| Sodium/potassium-transporting ATPase subunit alpha-1 | ATP1A1 | 2.72E+01 | 4.39E-04 |
| Ribosome biogenesis protein BMS1 homolog | BMS1 | 2.90E+01 | 8.92E-03 |
| Ribosome biogenesis protein BRX1 homolog | BRIX1 | 2.68E+01 | 1.41E-02 |
| Caprin-1 | CAPRIN1 | 2.80E+01 | 5.88E-03 |
| Coiled-coil domain-containing protein 124 | CCDC124 | 2.94E+01 | 1.91E-04 |
| T-complex protein 1 subunit gamma | CCT3 | 2.63E+01 | 4.86E-02 |
| T-complex protein 1 subunit epsilon | CCT5 | 2.64E+01 | 1.42E-03 |
| Cell division cycle 5-like protein | CDC5L | 3.04E+01 | 3.51E-03 |
| Centrosomal protein of 170 kDa | CEP170 | 2.71E+01 | 2.53E-03 |
| Chromatin target of PRMT1 protein | CHTOP | 2.81E+01 | 3.45E-02 |
| CLIP-associating protein 2 | CLASP2 | 2.74E+01 | 4.83E-03 |
| Methylosome subunit pICln | CLNS1A | 2.97E+01 | 2.16E-03 |
| Coatomer subunit gamma-2 | COPG2 | 2.59E+01 | 2.98E-04 |
| Coronin-1C | CORO1C | 3.03E+01 | 2.00E-02 |
| Cleavage and polyadenylation specificity factor subunit 6 | CPSF6 | 2.93E+01 | 4.13E-03 |
| Cleavage and polyadenylation specificity factor subunit 7 | CPSF7 | 2.73E+01 | 2.20E-03 |
| Probable ATP-dependent RNA helicase DDX17 | DDX17 | 3.22E+01 | 1.28E-02 |
| Probable ATP-dependent RNA helicase DDX20 | DDX20 | 2.73E+01 | 2.81E-02 |
| Nucleolar RNA helicase 2 | DDX21 | 3.01E+01 | 8.42E-03 |
| Probable ATP-dependent RNA helicase DDX23 | DDX23 | 2.93E+01 | 4.58E-03 |
| ATP-dependent RNA helicase DDX3X | DDX3X | 2.66E+01 | 5.42E-04 |
| Probable ATP-dependent RNA helicase DDX41 | DDX41 | 2.73E+01 | 4.88E-03 |
| Probable ATP-dependent RNA helicase DDX5 | DDX5 | 2.97E+01 | 1.38E-02 |
| ATP-dependent RNA helicase DDX50 | DDX50 | 2.65E+01 | 5.75E-03 |
| Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 | DHX15 | 2.76E+01 | 6.67E-03 |
| Putative ATP-dependent RNA helicase DHX30 | DHX30 | 2.99E+01 | 1.03E-02 |
| ATP-dependent RNA helicase A | DHX9 | 7.63E+00 | 4.50E-03 |
| Elongation factor 2 | EEF2 | 4.68E+00 | 8.14E-03 |
| 116 kDa U5 small nuclear ribonucleoprotein component | EFTUD2 | 3.04E+01 | 6.54E-03 |
| Eukaryotic translation initiation factor 3 subunit A | EIF3A | 3.34E+01 | 2.89E-04 |
| Eukaryotic translation initiation factor 3 subunit B | EIF3B | 3.19E+01 | 6.22E-03 |
| Eukaryotic translation initiation factor 3 subunit C | EIF3C | 3.23E+01 | 1.43E-03 |
| Eukaryotic translation initiation factor 3 subunit D | EIF3D | 3.01E+01 | 1.72E-03 |
| Eukaryotic translation initiation factor 3 subunit E | EIF3E | 3.15E+01 | 2.60E-03 |
| Eukaryotic translation initiation factor 3 subunit F | EIF3F | 3.08E+01 | 9.00E-03 |
| Eukaryotic translation initiation factor 3 subunit G | EIF3G | 2.99E+01 | 1.64E-04 |
| Eukaryotic translation initiation factor 3 subunit I | EIF3I | 3.07E+01 | 4.95E-03 |
| Eukaryotic translation initiation factor 3 subunit J | EIF3J | 2.75E+01 | 2.97E-04 |
| Eukaryotic translation initiation factor 3 subunit K | EIF3K | 2.75E+01 | 4.35E-02 |
| Eukaryotic translation initiation factor 3 subunit L | EIF3L | 3.20E+01 | 1.62E-03 |
| Eukaryotic translation initiation factor 3 subunit M | EIF3M | 3.06E+01 | 2.52E-02 |
| Eukaryotic translation initiation factor 3 subunit H | EIF3S3 | 2.98E+01 | 4.34E-03 |
| Eukaryotic initiation factor 4A-I | EIF4A1 | 2.82E+01 | 1.28E-02 |
| Eukaryotic initiation factor 4A-III | EIF4A3 | 2.66E+01 | 2.37E-02 |
| Eukaryotic translation initiation factor 4B | EIF4B | 3.07E+01 | 1.05E-02 |
| Eukaryotic translation initiation factor 6 | EIF6 | 2.71E+01 | 1.74E-02 |
| Emerin | EMD | 2.73E+01 | 1.99E-02 |
| Erlin-2 | ERLIN2 | 2.81E+01 | 7.54E-03 |
| Exosome component 10 | EXOSC10 | 2.76E+01 | 3.45E-03 |
| Exosome complex component RRP45 | EXOSC9 | 2.59E+01 | 2.53E-02 |
| Constitutive coactivator of PPAR-gamma-like protein 1 | FAM120A | 2.74E+01 | 1.36E-02 |
| Phenylalanine--tRNA ligase alpha subunit | FARSA | 2.78E+01 | 7.54E-03 |
| Phenylalanine--tRNA ligase beta subunit | FARSB | 2.78E+01 | 1.17E-02 |
| 40S ribosomal protein S30 | FAU | 2.85E+01 | 2.31E-03 |
| Protein furry homolog-like | FRYL | 3.02E+01 | 2.54E-02 |
| Gem-associated protein 4 | GEMIN4 | 2.71E+01 | 2.53E-03 |
| Guanine nucleotide-binding protein subunit beta-2-like 1 | GNB2L1 | 3.25E+01 | 3.47E-04 |
| Nucleolar GTP-binding protein 2 | GNL2 | 2.75E+01 | 7.11E-03 |
| Guanine nucleotide-binding protein-like 3 | GNL3 | 2.69E+01 | 4.03E-04 |
| Golgin subfamily A member 3 | GOLGA3 | 2.93E+01 | 3.96E-03 |
| General transcription factor 3C polypeptide 2 | GTF3C2 | 2.75E+01 | 3.97E-03 |
| General transcription factor 3C polypeptide 3 | GTF3C3 | 2.57E+01 | 3.56E-02 |
| General transcription factor 3C polypeptide 4 | GTF3C4 | 2.70E+01 | 2.46E-03 |
| Nucleolar GTP-binding protein 1 | GTPBP4 | 2.87E+01 | 1.26E-02 |
| Histone H2B | HIST1H2BN | 2.99E+01 | 1.62E-02 |
| Heterogeneous nuclear ribonucleoproteins C1/C2 | HNRNPC | 3.08E+01 | 3.22E-04 |
| Heterogeneous nuclear ribonucleoprotein D0 | HNRNPD | 2.60E+01 | 2.60E-02 |
| Heterogeneous nuclear ribonucleoprotein F | HNRNPF | 2.74E+01 | 4.67E-03 |
| Heterogeneous nuclear ribonucleoprotein K | HNRNPK | 2.96E+01 | 9.43E-04 |
| Heterogeneous nuclear ribonucleoprotein M | HNRNPM | 6.56E+00 | 1.98E-02 |
| Heterogeneous nuclear ribonucleoprotein R | HNRNPR | 2.99E+01 | 4.29E-03 |
| Heterogeneous nuclear ribonucleoprotein U | HNRNPU | 3.23E+01 | 2.34E-03 |
| Isoleucine--tRNA ligase, cytoplasmic | IARS | 2.72E+01 | 3.12E-03 |
| Insulin-like growth factor 2 mRNA-binding protein 1 | IGF2BP1 | 3.18E+01 | 1.09E-03 |
| Insulin-like growth factor 2 mRNA-binding protein 3 | IGF2BP3 | 2.81E+01 | 1.22E-02 |
| Interleukin enhancer-binding factor 2 | ILF2 | 3.10E+01 | 1.08E-02 |
| Interleukin enhancer-binding factor 3 | ILF3 | 3.27E+01 | 2.99E-03 |
| Importin-8 | IPO8 | 2.74E+01 | 1.30E-02 |
| Insulin receptor substrate 4 | IRS4 | 1.33E+00 | 3.38E-03 |
| Influenza virus NS1A-binding protein | IVNS1ABP | 3.33E+01 | 3.05E-03 |
| Tyrosine-protein kinase JAK1 | JAK1 | 2.88E+01 | 4.64E-03 |
| BTB/POZ domain-containing protein KCTD17 | KCTD17 | 2.96E+01 | 1.23E-02 |
| BTB/POZ domain-containing protein KCTD5 | KCTD5 | 2.96E+01 | 3.67E-04 |
| Kinesin-like protein KIF11 | KIF11 | 1.48E+00 | 1.25E-03 |
| La-related protein 1 | LARP1 | 3.17E+01 | 9.37E-04 |
| La-related protein 4 | LARP4 | 2.86E+01 | 7.22E-03 |
| La-related protein 4B | LARP4B | 2.65E+01 | 8.21E-03 |
| LIM domain and actin-binding protein 1 | LIMA1 | 2.98E+01 | 7.34E-03 |
| Leucine-rich PPR motif-containing protein, mitochondrial | LRPPRC | 2.63E+01 | 8.82E-03 |
| Putative RNA-binding protein Luc7-like 2 | LUC7L2 | 3.00E+01 | 3.39E-03 |
| Luc7-like protein 3 | LUC7L3 | 2.81E+01 | 5.20E-03 |
| Microtubule-associated protein 1B | MAP1B | 3.01E+01 | 3.76E-03 |
| Serine/threonine-protein kinase MARK2 | MARK2 | 2.60E+01 | 3.76E-03 |
| Methionine--tRNA ligase, cytoplasmic | MARS | 2.62E+01 | 1.62E-03 |
| Matrin-3 | MATR3 | 2.87E+01 | 1.32E-03 |
| DNA replication licensing factor MCM7 | MCM7 | 2.83E+01 | 8.19E-03 |
| E3 ubiquitin-protein ligase Midline-1 | MID1 | 3.76E+01 | 3.26E-04 |
| Putative helicase MOV-10 | MOV10 | 2.77E+01 | 2.49E-02 |
| 28S ribosomal protein S17, mitochondrial | MRPS17 | 2.91E+01 | 6.96E-03 |
| 28S ribosomal protein S22, mitochondrial | MRPS22 | 2.74E+01 | 4.69E-03 |
| 28S ribosomal protein S25, mitochondrial | MRPS25 | 2.71E+01 | 1.14E-02 |
| 28S ribosomal protein S27, mitochondrial | MRPS27 | 2.64E+01 | 3.48E-02 |
| Protein LYRIC | MTDH | 2.72E+01 | 1.03E-02 |
| Myb-binding protein 1A | MYBBP1A | 2.90E+01 | 1.44E-04 |
| Myosin-10 | MYH10 | 1.13E+00 | 2.28E-02 |
| Myosin-9 | MYH9 | 2.92E+01 | 4.78E-03 |
| Unconventional myosin-Ib | MYO1B | 2.71E+01 | 2.88E-02 |
| Nicotinamide phosphoribosyltransferase | NAMPT | 2.75E+01 | 8.55E-03 |
| Nucleosome assembly protein 1-like 1 | NAP1L1 | 2.57E+01 | 7.18E-03 |
| Nuclear cap-binding protein subunit 1 | NCBP1 | 2.81E+01 | 4.89E-04 |
| Nucleolin | NCL | 2.86E+01 | 6.74E-03 |
| Nucleolar complex protein 4 homolog | NOC4L | 2.80E+01 | 8.27E-03 |
| Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase | NOP2 | 2.62E+01 | 5.08E-03 |
| Cleavage and polyadenylation specificity factor subunit 5 | NUDT21 | 2.96E+01 | 6.21E-04 |
| OTU domain-containing protein 4 | OTUD4 | 2.74E+01 | 1.45E-03 |
| Prolyl 4-hydroxylase subunit alpha-1 | P4HA1 | 2.79E+01 | 4.44E-03 |
| Proliferation-associated protein 2G4 | PA2G4 | 3.08E+01 | 7.55E-03 |
| Polyadenylate-binding protein 1 | PABPC1 | 3.23E+01 | 2.17E-03 |
| Polyadenylate-binding protein 4 | PABPC4 | 3.22E+01 | 2.78E-03 |
| Programmed cell death protein 4 | PDCD4 | 2.94E+01 | 8.37E-03 |
| Proline-, glutamic acid- and leucine-rich protein 1 | PELP1 | 2.66E+01 | 9.09E-03 |
| Serine/threonine-protein phosphatase PGAM5, mitochondrial | PGAM5 | 2.86E+01 | 3.52E-03 |
| Protein arginine N-methyltransferase 5 | PRMT5 | 3.54E+01 | 6.16E-04 |
| Pre-mRNA-processing factor 19 | PRPF19 | 3.02E+01 | 3.67E-03 |
| U4/U6 small nuclear ribonucleoprotein Prp3 | PRPF3 | 2.70E+01 | 1.69E-02 |
| U4/U6 small nuclear ribonucleoprotein Prp31 | PRPF31 | 2.97E+01 | 8.19E-04 |
| U4/U6 small nuclear ribonucleoprotein Prp4 | PRPF4 | 2.64E+01 | 3.83E-03 |
| Pre-mRNA-processing factor 6 | PRPF6 | 2.98E+01 | 6.12E-03 |
| Pre-mRNA-processing-splicing factor 8 | PRPF8 | 3.11E+01 | 3.06E-03 |
| Ribose-phosphate pyrophosphokinase 1 | PRPS1 | 5.58E+00 | 3.60E-03 |
| Ribose-phosphate pyrophosphokinase 2 | PRPS2 | 2.93E+01 | 1.56E-02 |
| Phosphoribosyl pyrophosphate synthase-associated protein 1 | PRPSAP1 | 3.05E+01 | 8.50E-03 |
| Phosphoribosyl pyrophosphate synthase-associated protein 2 | PRPSAP2 | 3.25E+01 | 2.15E-04 |
| Protein PRRC2A | PRRC2A | 2.85E+01 | 8.43E-03 |
| Protein PRRC2C | PRRC2C | 2.97E+01 | 2.05E-02 |
| 26S protease regulatory subunit 4 | PSMC1 | 2.97E+01 | 5.78E-03 |
| 26S protease regulatory subunit 7 | PSMC2 | 3.07E+01 | 8.06E-04 |
| 26S protease regulatory subunit 6A | PSMC3 | 2.89E+01 | 5.50E-03 |
| 26S protease regulatory subunit 6B | PSMC4 | 1.19E+00 | 1.54E-02 |
| 26S protease regulatory subunit 8 | PSMC5 | 4.55E+00 | 3.71E-04 |
| 26S protease regulatory subunit 10B | PSMC6 | 2.84E+01 | 1.52E-03 |
| 26S proteasome non-ATPase regulatory subunit 1 | PSMD1 | 2.97E+01 | 2.12E-03 |
| 26S proteasome non-ATPase regulatory subunit 10 | PSMD10 | 2.85E+01 | 2.02E-02 |
| 26S proteasome non-ATPase regulatory subunit 11 | PSMD11 | 3.02E+01 | 1.94E-02 |
| 26S proteasome non-ATPase regulatory subunit 12 | PSMD12 | 2.90E+01 | 4.18E-03 |
| 26S proteasome non-ATPase regulatory subunit 13 | PSMD13 | 2.95E+01 | 3.11E-03 |
| 26S proteasome non-ATPase regulatory subunit 14 | PSMD14 | 2.80E+01 | 1.85E-03 |
| 26S proteasome non-ATPase regulatory subunit 2 | PSMD2 | 2.15E+00 | 4.38E-03 |
| 26S proteasome non-ATPase regulatory subunit 3 | PSMD3 | 3.04E+01 | 1.48E-04 |
| 26S proteasome non-ATPase regulatory subunit 4 | PSMD4 | 2.79E+01 | 1.70E-04 |
| 26S proteasome non-ATPase regulatory subunit 6 | PSMD6 | 2.96E+01 | 9.65E-03 |
| 26S proteasome non-ATPase regulatory subunit 7 | PSMD7 | 3.75E+00 | 1.13E-02 |
| 26S proteasome non-ATPase regulatory subunit 8 | PSMD8 | 2.75E+01 | 1.56E-03 |
| Poly(U)-binding-splicing factor PUF60 | PUF60 | 2.75E+01 | 9.95E-04 |
| Pyrroline-5-carboxylate reductase | PYCR1 | 2.55E+01 | 3.49E-03 |
| RNA-binding protein 10 | RBM10 | 3.30E+01 | 4.88E-04 |
| RNA-binding protein 14 | RBM14 | 2.94E+01 | 6.57E-03 |
| RNA-binding protein 25 | RBM25 | 2.75E+01 | 7.71E-03 |
| RNA-binding protein 26 | RBM26 | 2.63E+01 | 3.79E-02 |
| RNA-binding protein 27 | RBM27 | 2.70E+01 | 1.20E-02 |
| RNA-binding protein 28 | RBM28 | 2.63E+01 | 5.02E-03 |
| RNA-binding motif protein, X chromosome | RBMX | 3.01E+01 | 8.90E-03 |
| RNA 3-terminal phosphate cyclase-like protein | RCL1 | 2.65E+01 | 1.64E-03 |
| Reticulocalbin-2 | RCN2 | 2.73E+01 | 2.67E-03 |
| Replication factor C subunit 3 | RFC3 | 2.62E+01 | 2.34E-02 |
| Telomere-associated protein RIF1 | RIF1 | 3.04E+01 | 9.16E-03 |
| Serine/threonine-protein kinase RIO1 | RIOK1 | 3.02E+01 | 3.05E-03 |
| RING finger protein 219 | RNF219 | 2.94E+01 | 2.50E-03 |
| RNA-binding protein 39 | RNPC2 | 2.86E+01 | 8.92E-03 |
| 60S ribosomal protein L10 | RPL10 | 3.26E+01 | 7.84E-03 |
| 60S ribosomal protein L10a | RPL10A | 3.22E+01 | 2.24E-02 |
| 60S ribosomal protein L11 | RPL11 | 3.19E+01 | 1.04E-03 |
| 60S ribosomal protein L12 | RPL12 | 3.18E+01 | 6.43E-03 |
| 60S ribosomal protein L13 | RPL13 | 3.30E+01 | 4.30E-04 |
| 60S ribosomal protein L13a | RPL13A | 3.17E+01 | 2.25E-03 |
| 60S ribosomal protein L14 | RPL14 | 3.07E+01 | 7.88E-04 |
| 60S ribosomal protein L15 | RPL15 | 5.67E+00 | 8.90E-03 |
| 60S ribosomal protein L17 | RPL17 | 3.16E+01 | 4.69E-04 |
| 60S ribosomal protein L18 | RPL18 | 3.28E+01 | 1.68E-03 |
| 60S ribosomal protein L18a | RPL18A | 3.24E+01 | 2.10E-03 |
| Ribosomal protein L19 | RPL19 | 3.26E+01 | 4.36E-03 |
| 60S ribosomal protein L21 | RPL21 | 3.11E+01 | 1.99E-03 |
| 60S ribosomal protein L22 | RPL22 | 3.05E+01 | 1.47E-03 |
| 60S ribosomal protein L22-like 1 | RPL22L1 | 2.70E+01 | 6.60E-03 |
| 60S ribosomal protein L23 | RPL23 | 3.09E+01 | 4.70E-03 |
| 60S ribosomal protein L23a | RPL23A | 3.24E+01 | 1.26E-03 |
| 60S ribosomal protein L24 | RPL24 | 3.03E+01 | 1.24E-03 |
| 60S ribosomal protein L26 | RPL26 | 3.24E+01 | 1.20E-03 |
| 60S ribosomal protein L27 | RPL27 | 3.18E+01 | 3.06E-03 |
| 60S ribosomal protein L27a | RPL27A | 3.06E+01 | 5.33E-04 |
| 60S ribosomal protein L28 | RPL28 | 3.22E+01 | 6.23E-04 |
| 60S ribosomal protein L29 | RPL29 | 3.19E+01 | 3.76E-04 |
| 60S ribosomal protein L3 | RPL3 | 7.15E+00 | 6.72E-03 |
| 60S ribosomal protein L30 | RPL30 | 3.04E+01 | 2.06E-03 |
| 60S ribosomal protein L31 | RPL31 | 3.15E+01 | 3.12E-04 |
| 60S ribosomal protein L32 | RPL32 | 3.18E+01 | 3.51E-04 |
| 60S ribosomal protein L34 | RPL34 | 2.90E+01 | 4.73E-03 |
| 60S ribosomal protein L35 | RPL35 | 3.13E+01 | 1.43E-02 |
| 60S ribosomal protein L35a | RPL35A | 3.14E+01 | 2.01E-02 |
| 60S ribosomal protein L36 | RPL36 | 3.02E+01 | 1.49E-02 |
| 60S ribosomal protein L36a | RPL36A | 2.97E+01 | 5.51E-04 |
| 60S ribosomal protein L37a | RPL37A | 3.07E+01 | 1.05E-04 |
| 60S ribosomal protein L38 | RPL38 | 2.90E+01 | 3.49E-02 |
| 60S ribosomal protein L4 | RPL4 | 3.36E+01 | 1.82E-03 |
| 60S ribosomal protein L5 | RPL5 | 3.26E+01 | 6.62E-03 |
| 60S ribosomal protein L6 | RPL6 | 6.39E+00 | 9.35E-03 |
| 60S ribosomal protein L7 | RPL7 | 3.33E+01 | 2.21E-03 |
| 60S ribosomal protein L7a | RPL7A | 8.22E+00 | 1.74E-03 |
| 60S ribosomal protein L8 | RPL8 | 3.33E+01 | 9.73E-04 |
| 60S ribosomal protein L9 | RPL9 | 3.06E+01 | 1.10E-04 |
| 60S acidic ribosomal protein P0 | RPLP0 | 3.23E+01 | 2.18E-03 |
| 60S acidic ribosomal protein P2 | RPLP2 | 2.87E+01 | 4.32E-03 |
| 40S ribosomal protein S10 | RPS10 | 3.21E+01 | 1.86E-03 |
| 40S ribosomal protein S11 | RPS11 | 3.24E+01 | 1.88E-03 |
| 40S ribosomal protein S12 | RPS12 | 3.14E+01 | 4.05E-04 |
| 40S ribosomal protein S13 | RPS13 | 3.22E+01 | 1.60E-03 |
| 40S ribosomal protein S14 | RPS14 | 3.15E+01 | 4.92E-04 |
| 40S ribosomal protein S15 | RPS15 | 3.15E+01 | 3.33E-02 |
| 40S ribosomal protein S15a | RPS15A | 3.19E+01 | 1.70E-03 |
| 40S ribosomal protein S16 | RPS16 | 3.24E+01 | 1.08E-03 |
| 40S ribosomal protein S17 | RPS17 | 3.19E+01 | 1.78E-03 |
| 40S ribosomal protein S18 | RPS18 | 8.03E+00 | 7.90E-09 |
| 40S ribosomal protein S19 | RPS19 | 3.22E+01 | 1.65E-03 |
| 40S ribosomal protein S2 | RPS2 | 3.28E+01 | 1.71E-03 |
| 40S ribosomal protein S20 | RPS20 | 3.21E+01 | 4.89E-04 |
| 40S ribosomal protein S21 | RPS21 | 2.88E+01 | 2.47E-03 |
| 40S ribosomal protein S23 | RPS23 | 3.25E+01 | 1.31E-03 |
| 40S ribosomal protein S24 | RPS24 | 3.00E+01 | 1.10E-04 |
| 40S ribosomal protein S25 | RPS25 | 3.14E+01 | 5.19E-03 |
| 40S ribosomal protein S26 | RPS26 | 3.08E+01 | 2.54E-02 |
| 40S ribosomal protein S27 | RPS27 | 3.00E+01 | 3.65E-03 |
| 40S ribosomal protein S3 | RPS3 | 3.28E+01 | 3.26E-03 |
| 40S ribosomal protein S3a | RPS3A | 3.30E+01 | 4.75E-04 |
| 40S ribosomal protein S4, X isoform | RPS4X | 6.65E+00 | 2.28E-03 |
| 40S ribosomal protein S6 | RPS6 | 3.18E+01 | 2.28E-03 |
| 40S ribosomal protein S7 | RPS7 | 3.28E+01 | 1.99E-02 |
| 40S ribosomal protein S8 | RPS8 | 3.24E+01 | 3.63E-03 |
| 40S ribosomal protein S9 | RPS9 | 3.31E+01 | 3.94E-03 |
| 40S ribosomal protein SA | RPSA | 3.32E+01 | 1.29E-03 |
| Ribosome-binding protein 1 | RRBP1 | 2.84E+01 | 3.20E-02 |
| RRP12-like protein | RRP12 | 2.58E+01 | 1.13E-02 |
| Ribosomal L1 domain-containing protein 1 | RSL1D1 | 2.69E+01 | 1.56E-02 |
| U4/U6.U5 tri-snRNP-associated protein 1 | SART1 | 2.91E+01 | 1.18E-04 |
| Splicing factor, arginine/serine-rich 15 | SCAF4 | 2.74E+01 | 1.68E-02 |
| Protein SDA1 homolog | SDAD1 | 2.64E+01 | 1.69E-02 |
| Plasminogen activator inhibitor 1 RNA-binding protein | SERBP1 | 3.28E+01 | 2.19E-02 |
| Splicing factor 3B subunit 1 | SF3B1 | 2.81E+01 | 8.87E-03 |
| Splicing factor 3B subunit 3 | SF3B3 | 2.72E+01 | 1.14E-02 |
| Superkiller viralicidic activity 2-like 2 | SKIV2L2 | 2.75E+01 | 8.05E-03 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | SNRNP200 | 3.06E+01 | 5.98E-03 |
| U5 small nuclear ribonucleoprotein 40 kDa protein | SNRNP40 | 2.72E+01 | 1.41E-02 |
| Small nuclear ribonucleoprotein Sm D1 | SNRPD1 | 3.02E+01 | 1.48E-03 |
| Small nuclear ribonucleoprotein Sm D2 | SNRPD2 | 2.92E+01 | 2.94E-04 |
| Small nuclear ribonucleoprotein Sm D3 | SNRPD3 | 2.95E+01 | 1.93E-02 |
| Small nuclear ribonucleoprotein-associated proteins B and B | SNRPN | 3.06E+01 | 4.62E-04 |
| Spectrin alpha chain, non-erythrocytic 1 | SPTAN1 | 3.41E+01 | 9.63E-04 |
| Spectrin beta chain, non-erythrocytic 1 | SPTBN1 | 3.41E+01 | 9.41E-05 |
| SRSF protein kinase 1 | SRPK1 | 2.94E+01 | 5.81E-03 |
| SRSF protein kinase 2 | SRPK2 | 2.60E+01 | 2.88E-02 |
| Serine/arginine repetitive matrix protein 1 | SRRM1 | 2.85E+01 | 1.46E-02 |
| Serrate RNA effector molecule homolog | SRRT | 2.57E+01 | 2.04E-03 |
| Serine/arginine-rich splicing factor 1 | SRSF1 | 2.74E+01 | 1.86E-04 |
| Serine/arginine-rich splicing factor 2 | SRSF2 | 2.69E+01 | 4.59E-02 |
| Serine/arginine-rich splicing factor 3 | SRSF3 | 2.87E+01 | 1.42E-03 |
| Double-stranded RNA-binding protein Staufen homolog 1 | STAU1 | 2.88E+01 | 1.18E-02 |
| Serine/threonine-protein kinase 38 | STK38 | 2.78E+01 | 2.59E-02 |
| SUN domain-containing protein 2 | SUN2 | 2.97E+01 | 6.35E-04 |
| Heterogeneous nuclear ribonucleoprotein Q | SYNCRIP | 2.82E+01 | 1.08E-02 |
| Very-long-chain enoyl-CoA reductase | TECR | 2.70E+01 | 4.59E-03 |
| Testis-expressed sequence 10 protein | TEX10 | 2.64E+01 | 1.64E-03 |
| THO complex subunit 2 | THOC2 | 2.53E+01 | 1.37E-02 |
| Tight junction protein ZO-2 | TJP2 | 2.65E+01 | 6.69E-03 |
| Transmembrane protein 33 | TMEM33 | 2.74E+01 | 1.11E-02 |
| Tropomodulin-3 | TMOD3 | 2.63E+01 | 4.62E-03 |
| TRMT1-like protein | TRMT1L | 2.82E+01 | 9.34E-03 |
| Tubulin beta-3 chain | TUBB3 | 2.57E+01 | 5.04E-04 |
| Tubulin beta-4A chain | TUBB4A | 2.61E+01 | 2.90E-02 |
| Splicing factor U2AF 35 kDa subunit | U2AF1 | 2.90E+01 | 7.02E-03 |
| Splicing factor U2AF 65 kDa subunit | U2AF2 | 2.98E+01 | 4.30E-03 |
| U2 snRNP-associated SURP motif-containing protein | U2SURP | 2.78E+01 | 1.78E-05 |
| E3 ubiquitin-protein ligase UBR5 | UBR5 | 2.78E+01 | 2.75E-02 |
| U4/U6.U5 tri-snRNP-associated protein 2 | USP39 | 2.88E+01 | 2.14E-02 |
| Transitional endoplasmic reticulum ATPase | VCP | 2.80E+01 | 7.61E-05 |
| Vimentin | VIM | 1.35E+00 | 2.08E-02 |
| Methylosome protein 50 | WDR77 | 3.30E+01 | 2.27E-02 |
| Exportin-T | XPOT | 2.64E+01 | 7.27E-03 |
| Nuclease-sensitive element-binding protein 1 | YBX1 | 3.07E+01 | 3.00E-03 |
| YTH domain-containing protein 1 | YTHDC1 | 2.78E+01 | 8.82E-03 |
| YTH domain-containing family protein 2 | YTHDF2 | 1.60E+00 | 3.42E-02 |
| Zinc finger CCCH domain-containing protein 18 | ZC3H18 | 2.79E+01 | 1.14E-02 |
| Zinc finger CCCH-type antiviral protein 1 | ZC3HAV1 | 2.79E+01 | 1.27E-02 |
| Zinc finger protein 622 | ZNF622 | 2.75E+01 | 1.14E-02 |
Log2 ratio and p-values were calculated using measured protein intensities, i.e. eXtracted Ion Current (XIC) of all isotopic clusters associated with the identified amino acid sequence. Log2 ratio was calculated from the intensity sum of samples/ controls. p-values are the result of a two-sided t-test, samples vs. control. In cases where intensities had been measured in 2 (out of 3) replicates, the third intensity value was added through imputation. If no intensity could be measured in all 3 replicates, the intensities were set from 0 to 1 in order to still be able to calculate a ratio (same applies to cases where only 1 intensity could be measured)