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. 2018 Feb 9;4:14. doi: 10.1038/s41420-017-0014-5

Fig. 2. Signs of loss of β-cell features.

Fig. 2

a The proportion of human islet cells expressing transcripts relevant for β-cell functional machinery. b qPCR analyses on HLXB9, PDX1, NKX6.1, and MAFA transcripts in islet and non-islet fractions. c The proportion of human islet cells expressing β-cell transcription factor transcripts. Pink arbitrarily indicates moderately low % and red arbitrarily indicates low %. d Co-immunostaining for C-pep and CHGA or PDX1 in human islet cells. DAPI stains for nuclei. Scale Bar: 50 μm