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. 2018 Mar 5;2018:bay018. doi: 10.1093/database/bay018

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© The Author(s) 2018. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Variation distribution according to physiochemical properties. Left top: mutability distribution for all NDDs in 36 variation situations: number 1–6 denotes to 6 groups of amino acids according to their physiochemical properties: (1) hydrophobic (V, I, L, F, M, W, Y, C), (2) negatively charged (D, E), (3) positively charged (R, K, H), (4) conformational (G, P), (5) polar (N, Q, S) and (6) Alanine and Threonine (A, T) group. The same information for Myotonia Congenita (MC), Dystonia Musculorum Deformans (DMD) and Hereditary Sensory and Frontotemporal Lobar Degeneration (FTLD) are displayed in the right top, left and right bottoms, respectively.