Table 1.
Patient | Resistance to >2AEDs | Age at surgery (yrs) | Duration of epilepsy (from onset; yrs) | Seizure frequency (n/mo) | AEDs at surgery | Hippocampal pathology | |
---|---|---|---|---|---|---|---|
CPH | 1 | Yes | 52 | 25 | 1 (KFA) | LTG, LEV | HS |
CPH | 2 | Yes | 54 | 14 | 5 (KFA) | LEV, LTG | HS |
CPH | 3 | Yes | 41 | 34 | 8 (SFA), 5 (KFA) | ZNS, LAC, CLB | HS |
Lund | 4 | Yes | 36 | 35 | 5 | LTG, VPA | HS |
CPH | 5 | Yes | 55 | 19 | 8 (SFA), 4 (KFA) | LEV, LAC | HS |
CPH | 6 | Yes | 31 | 12 | 1 (SFA), 1 (KFA) | LTG, LEV | HS |
CPH | 7 | Yes | 57 | 5 | 9 (KFA) | OXC | HS |
CPH | 8 | Yes | 34 | 8 | 3 (KFA) | CBZ, LEV, LAC | HS |
Lund | 9 | Yes | 28 | 16 | 3 | LTG, LEV | Normal |
CPH | 10 | Yes | 18 | 12 | 8 (SFA), 8 (KFA) | VPA | HS |
CPH | 12 | Yes | 44 | 16 | 5 | BV, ZNS, LTG | Normal |
CPH | 13 | Yes | 19 | 13 | 6 (SFA) 6 (KFA) | LEV, CBZ | HS |
Lund | 14 | Yes | 23 | 22 | 4 (KFA) | LEV, LAC | HS |
CPH | 15 | Yes | 36 | 26 | 12 (SFA), 12 (KFA) | LTG, LEV | HS |
Lund | 16 | Yes | 6 | 5 | 30 | LTG, LEV | HS |
Seizure frequency reported by patients in Copenhagen (CPH) reported as simple focal seizures (SFS) and complex focal seizures (CFS). If SFS are not noted the patient does not report experiencing auras/SFS. Abbreviations as follows carbamazepine (CBZ), clobazam (CLB), Brivaracetam (BV), lacosamide (LAC), lamotrigine (LTG), levetiracetam (LEV), oxcarbazepine (OXC), valproate (VPA) and zonesamide (ZNS) and hippocampal sclerosis abbreviated as (HS).