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. 2018 Mar 7;8:4110. doi: 10.1038/s41598-018-22527-y

Figure 4.

Figure 4

Conformational itinerary of −1 MurNAc along MltE transformation. I denotes the Michaelis complex; Ts12D, the transition species between I and II2D; II2D, the intermediate; Ts22D, the transition species between II2D and III2D; III2D and IIIQM, the 1,6-anhydroMurNAc in the B3,O conformation; Ts3QM, the transition species between IIIQM and IVQM; IVQM, the 1,6-anhydroMurNAc in the 1C4 conformation. A −1 MurNAc adopts boat (B), chair (C), envelope (E), and skew (S) conformations. The B3,O to 1C4 transformation is off-enzyme reaction.