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. 2018 Feb 16;5(1):e000197. doi: 10.1136/bmjgast-2017-000197

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Study design: treatment sequences and periods for sequence PCPP and sequence PPPC. P-CAB, potassium-competitive acid blocker; PCPP, P-CAB during period 1 and PPI during period 2; PPPC, PPI during period 1 and P-CAB during period 2; PPI, proton pump inhibitor.