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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Graefes Arch Clin Exp Ophthalmol. 2017 May 18;255(8):1581–1592. doi: 10.1007/s00417-017-3690-1

Figure 6.

Figure 6

Evaluation of inflammatory and vascular permeability markers. Representative Western blot illustrating TNFα (A), IL6 (B), IL1β (C), and VEGF (D). BMSC treatment significantly reduced levels of TNFα, IL1β, and IL6; and increased VEGF compared to PBS injected ischemic eyes. The bar graphs demonstrate the levels of all four proteins normalized to β-arrestin. (E) Bar graph exhibiting Evans Blue dye extravasation, marker of vascular permeability, in ischemic PBS and BMSC injected retina. Data are shown as mean ± SEM. * indicates P < 0.05 compared to the paired normal retina within a group (PBS or BMSC); # indicates P < 0.05 between the ischemic retinae of PBS and BMSC. N = 3–4 per group for Western blotting, and 7 for Evans Blue. See Figure 4 legend for abbreviations.