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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Surg Pathol Clin. 2017 Dec 8;11(1):123–145. doi: 10.1016/j.path.2017.09.009

Fig 13. Pleomorphic lobular carcinoma in situ, apocrine type.

Fig 13

Fig 13

a. H&E stain. b. Immunohistochemical stain for E-cadherin. The cells are dyshesive, with abundant eosinophilic granular cytoplasm, large nuclei, and prominent nucleoli. Instead of complete loss of E-cadherin expression, the cells composing PLCIS in this case show focal incomplete, attenuated, and granular membranous staining for E-cadherin. Magnification 200x.