Table 1. Minimum inhibitory concentrations (μg/ml) of Products A, B, C and commercial topical ophthalmic products against bacterial isolates.
MICs of the tested preparation in μg/ml. | ||||||
---|---|---|---|---|---|---|
Strain | A | B | C | Tobramycin | Gentamicin | Ofloxacin |
Moraxella bovis 80–2013000742 | 0.78 | ≥ 6.25 | ≥ 1500 | ≤ 0.36 | ≤ 0.36 | ≤ 0.36 |
Moraxella bovis 36–2012001922 | 6.25 | 6.25 | ≥ 1500 | ≤ 0.36 | ≤ 0.36 | ≤ 0.36 |
Moraxella bovis 120–2014002878 | 6.25 | ≥ 6.25 | ≥ 1500 | ≤ 0.36 | ≤ 0.36 | ≤ 0.36 |
Moraxella bovis 42–2012003587 | 6.25 | ≥ 6.25 | ≥ 1500 | ≤ 0.36 | ≤ 0.36 | ≤ 0.36 |
Neisseria spp. isolate 1 | 6.25 | 6.25 | ≥ 1500 | ≤ 11.7 | ≤ 11.7 | ≤ 11.7 |
Pseudomonas aeruginosa 15442 | 6.25 | 6.25 | ≥ 1500 | ≤ 0.36 | 0.73 | 0.73 |
Pseudomonas aeruginosa isolate 1 | 6.25 | 6.25 | ≥ 1500 | ≤ 0.36 | ≤ 0.36 | ≤ 0.36 |
Pseudomonas aeruginosa isolate 2 | 25 | 6.25 | ≥ 1500 | ≤ 0.36 | ≤ 0.36 | 5.8 |
Staphylococcus aureus isolate 1 | 6.25 | 6.25 | ≥ 1500 | ≤ 0.36 | ≤ 0.36 | ≤ 0.36 |
Staphylococcus aureus isolate 2 | 6.25 | 6.25 | ≥ 1500 | 0.73 | 0.73 | ≤ 0.36 |
Staphylococcus pseudintermedius Case one | 3.13 | 6.25 | ≥ 1500 | 11.7 | 23.4 | 23.4 |
Staphylococcus pseudintermedius Case two |
3.13 | 3.13 | ≥ 1500 | ≤ 11.7 | ≤ 0.391 | ≤ 0.391 |
Streptococcus canis isolate 1 | 12.5 | ≥ 6.25 | ≥ 1500 | 5.8 | 2.9 | 0.73 |
Streptococcus canis isolate 2 | 12.5 | ≥ 6.25 | ≥ 1500 | 11.7 | 5.8 | 0.73 |
Streptococcus canis isolate 3 | 12.5 | 6.25 | ≥ 1500 | 5.9 | 2.9 | 1.5 |
Streptococcus canis isolate 4 | 6.25 | ≥ 6.25 | ≥ 1500 | 11.7 | 5.8 | 0.73 |
Streptococcus schleiferi isolate 1 | 0.78 | ≥ 6.25 | ≥ 1500 | ≤ 0.36 | ≤ 0.36 | ≤ 0.36 |
All MIC values are recorded in μg/ml. Concentrations were calculated from the dilutions of the active ingredient in each of the original commercially available products.