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. 2018 Mar 7;13(3):e0193217. doi: 10.1371/journal.pone.0193217

Table 1. Minimum inhibitory concentrations (μg/ml) of Products A, B, C and commercial topical ophthalmic products against bacterial isolates.

MICs of the tested preparation in μg/ml.
Strain A B C Tobramycin Gentamicin Ofloxacin
Moraxella bovis 80–2013000742 0.78 ≥ 6.25 ≥ 1500 ≤ 0.36 ≤ 0.36 ≤ 0.36
Moraxella bovis 36–2012001922 6.25 6.25 ≥ 1500 ≤ 0.36 ≤ 0.36 ≤ 0.36
Moraxella bovis 120–2014002878 6.25 ≥ 6.25 ≥ 1500 ≤ 0.36 ≤ 0.36 ≤ 0.36
Moraxella bovis 42–2012003587 6.25 ≥ 6.25 ≥ 1500 ≤ 0.36 ≤ 0.36 ≤ 0.36
Neisseria spp. isolate 1 6.25 6.25 ≥ 1500 ≤ 11.7 ≤ 11.7 ≤ 11.7
Pseudomonas aeruginosa 15442 6.25 6.25 ≥ 1500 ≤ 0.36 0.73 0.73
Pseudomonas aeruginosa isolate 1 6.25 6.25 ≥ 1500 ≤ 0.36 ≤ 0.36 ≤ 0.36
Pseudomonas aeruginosa isolate 2 25 6.25 ≥ 1500 ≤ 0.36 ≤ 0.36 5.8
Staphylococcus aureus isolate 1 6.25 6.25 ≥ 1500 ≤ 0.36 ≤ 0.36 ≤ 0.36
Staphylococcus aureus isolate 2 6.25 6.25 ≥ 1500 0.73 0.73 ≤ 0.36
Staphylococcus pseudintermedius Case one 3.13 6.25 ≥ 1500 11.7 23.4 23.4
Staphylococcus pseudintermedius
Case two
3.13 3.13 ≥ 1500 ≤ 11.7 ≤ 0.391 ≤ 0.391
Streptococcus canis isolate 1 12.5 ≥ 6.25 ≥ 1500 5.8 2.9 0.73
Streptococcus canis isolate 2 12.5 ≥ 6.25 ≥ 1500 11.7 5.8 0.73
Streptococcus canis isolate 3 12.5 6.25 ≥ 1500 5.9 2.9 1.5
Streptococcus canis isolate 4 6.25 ≥ 6.25 ≥ 1500 11.7 5.8 0.73
Streptococcus schleiferi isolate 1 0.78 ≥ 6.25 ≥ 1500 ≤ 0.36 ≤ 0.36 ≤ 0.36

All MIC values are recorded in μg/ml. Concentrations were calculated from the dilutions of the active ingredient in each of the original commercially available products.