Table 2. BAGS assignment and time to treatment.
| Hazard ratio | 95% CI | P | |
|---|---|---|---|
| BAGS subtype | |||
| Memory | 1 | ||
| Pre-BI | 1.61 | 0.97 to 2.67 | 0.07 |
| Pre-BII | 3.67 | 1.82 to 7.38 | < 0.001 |
| Immature | 1.67 | 0.89 to 3.12 | 0.11 |
| Naïve | 1.23 | 0.78 to 1.94 | 0.37 |
| Plasma cell | 0.80 | 0.32 to 2.01 | 0.64 |
| Unclassified | 1.17 | 0.73 to 1.90 | 0.51 |
| BAGS subtype groupsa | |||
| Early | 1 | ||
| Naïve | 0.66 | 0.41 to 1.05 | 0.078 |
| Late | 0.53 | 0.35 to 0.78 | 0.002 |
| Unclassified | 0.63 | 0.38 to 1.03 | 0.067 |
aBAGS assignments for individual BAGS subtypes and grouped as early (BI, BII), NA, or late (ME, PC) were associated to outcome (time to treatment) using univariate Cox proportional hazards regression analysis. The Munich, IIDFI, and UCSD cohorts were used (n = 296).