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. 2018 Mar 7;13(3):e0193146. doi: 10.1371/journal.pone.0193146

Table 3. General characteristics and medication use at the four hospitals pre/post implementation.

Muhimbili National Hosp. KCMC Bugando Haydom
Pre-I Post-I P Value Pre-I Post-I P Value Pre-I Post-I P Value Pre-I Post-I P Value
159 2222 205 388 118 261 61 75
Birthweight (Grams) 1541 ±
322
1711 ± 416 <0.0001 1853 ± 484 1756 ± 457 0.016 1621 ± 339 1601 ± 334 0.59 1736 ± 373 1989 ± 31.6 <0.0001
Gestational Age (Weeks) 31.1 ±
2.1
31.9 ± 1.9 <0.0001 31.6 ± 2.1 31.69 ± 2 0.60 30.3 ± 1.36 30.28 ± 1.60 0.90 31.8 ± 1.9 31.6 ± 2.0 0.55
Inborn/
Referred
53/
106
784/
1296
0.30 102/
103
180/
208
0.43 114/
4
158/
29
0.0002 50/
11
60/
15
0.77
Mode of
Delivery
Vaginal 68 995 0.49 101 165 0.21 64 137 0.91 46 53 0.35
C-Section 80 1037 97 200 52 117 15 25
Vacuum 8 184 7 23 2 7 0 4
Gender
Male/
Female
73/
86
1048/
1170
0.74 102/
103
222/
166
0.08 60/
58
130/
131
0.85 26/
35
53/
22
0.002
Medications
Maternal Antibiotics 42
(26.4%)
1674 (75.3%) <0.0001 104 (50.7%) 295 (76%) <0.0001 14 (11.9%) 78 (29.9%) <0.0001 7 (11.5%) 24 (29%) 0.01
ACS 28
(17.6%)
1629 (73.3%) <0.0001 110 (53.7%) 222 (57%) 0.40 45 (38.1%) 195 (74.7%) <0.0001 2
(3.3%)
18 (22%) <0.0001
Neonatal Antibiotics 2
(1.3%)
1892 (85.1%) <0.0001 107 (52%) 298 (76.8%) <0.0001 32 (27.1%) 181 (69%) <0.0001 18 (29.5%) 51
(62%)
0.0001
Temperature
Measured
0 1780 (80%) 81
(39.5%)
297 (76.5%) <0.0001 58
(49%)
258 (99%) <0.0001 13
(21.3%)
50 (61%) <0.0001

I = Implementation, C-Section = Cesarean section, ACS = Antenatal Corticosteroids. KCMC = Kilimanjaro Christian Medical Center.Data were analyzed with Pearson Chi Square and student t tests where appropriate.