Table 4.
Significance (t-values) of regression coefficients of NSHD bone outcomes on SITAR parameters, without and with body size adjustment, sexes combined (n = 2321)
| Bone outcome | Trabecular vBMD |
Diaphysis CSA |
||
|---|---|---|---|---|
| Model | 1a | 2b | 1 | 2 |
| Height size | –2.4 | –1.3 | 2.6 | –1.6 |
| Height tempo | –3.4 | –3.6 | –0.2 | –0.1 |
| Height velocity | 1.0 | 0.8 | 1.3 | 1.2 |
| Weight size | –0.1 | 0.0 | 5.2 | 5.2 |
| Weight tempo | –0.5 | –0.1 | –2.2 | –2.5 |
| Weight velocity | 0.5 | –0.3 | –2.7 | –2.9 |
| Female sex | –15 | –4.1 | –47 | –11 |
| Height @ 60–64 | –0.4 | 4.0 | ||
| Weight @ 60–64 | 4.6 | 2.9 | ||
| Adjusted R2 (%) | 15.9 | 17.1 | 65.8 | 66.4 |
| Growth impact (%)c | 17.5 | 17.9 | 25.8 | 15.3 |
a Model 1: SITAR height and weight parameters plus sex.
b Model 2: as Model 1 plus height and weight at age 60–64 years.
c Impact on outcome attributable to growth pattern—see text.
Bone outcomes, height and weight are all log-transformed. SITAR parameter coefficients significant at P < 0.02 are shown in bold.