Figure 2. GPR81 agonism inhibits adipocyte lipolysis in vitro.

(A) Representative dose-response curve showing the ability of AZ1 to suppress forskolin-stimulated release of glycerol from primary rat adipocytes (EC₅₀ 58 nM) and (B) primary human adipocytes (EC₅₀ 550 nM). Results shown as the mean ± SEM, n = 5.