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. 2017 Oct 5;2(19):e95367. doi: 10.1172/jci.insight.95367

Figure 4. Results of 2 patients with EBV VCA–specific mc IgG.

Figure 4

For each patient, results obtained with the serum (S) and the purified monoclonal (mc) IgG are represented. (A) For patients P10 and P50, the serum contained IgG that recognized EBV nuclear antigen-1 (EBNA-1) and EBV viral capsid antigen (VCA), but the purified mc IgG recognized only EBV VCA. (B) Detail of results obtained for patient P10: serum P10 contained IgG that recognized B. burgdorferi, CMV, EBNA-1, EBV VCA, H. pylori, herpes simplex virus-2 (HSV-2), T. gondii, and varicella zoster virus (VZV), whereas the purified mc IgG recognized EBV VCA only. (C) Detail of results obtained for patient P50: serum P50 contained IgG that recognized CMV, EBNA-1, EBV VCA, HSV-2, and VZV, whereas the purified mc IgG recognized EBV VCA only. The fluorescence values shown for each pathogen, Ag, or lysate were obtained after subtraction of the threshold of specific positivity of the pathogen, Ag, or lysate (1,400 for EBV). Dots may be superimposed; horizontal bars represent the means of results obtained for a pathogen, Ag, or lysate. Experiments were performed at least twice.