Skip to main content
. 2017 Oct 5;2(19):e95367. doi: 10.1172/jci.insight.95367

Figure 5. HSV-1–specific mc IgG as determined by the MIAA assay.

Figure 5

(A) Results of the multiplex infectious-antigen array (MIAA) assay for the 7 patients found to have a herpes simplex virus-1–specific (HSV-1–specific) monoclonal (mc) IgG. For each patient, the results obtained for HSV-1 lysate and glycoprotein G (gG) with the patient’s serum (S) and with purified mc IgG (mc) are shown. (B) Detail of results obtained for patient P9: P9 serum contained IgG that recognized EBV nuclear antigen-1 (EBNA-1), EBV viral capsid antigen (VCA), CMV, HSV-1, varicella zoster virus (VZV), and T. gondii, whereas the purified mc IgG recognized only HSV-1 gG. The fluorescence values shown for each pathogen, Ag, or lysate were obtained after subtraction of the threshold of specific positivity of the pathogen, Ag, or lysate (1,000 for HSV-1). Dots may be superimposed; horizontal bars represent the means of results obtained for a pathogen, Ag, or lysate. Experiments were performed at least twice.