LFP detection – 3SD | MUA analysis | ||||||||||||||
WT | Dp16 | p-value | WT | Dp16 | p-value | ||||||||||
Spikes per ripple | 0.241 | ± | 0.009 | 0.218 | ± | 0.010 | 0.0041 | 0.204 | ± | 0.011 | 0.184 | ± | 0.010 | 0.0219 | |
Firing rate in ripple | 0.603 | ± | 0.022 | 0.546 | ± | 0.025 | 0.0041 | 0.509 | ± | 0.026 | 0.461 | ± | 0.024 | 0.0219 | |
Participation in ripple (%) | 15.807 | ± | 0.511 | 14.661 | ± | 0.591 | 0.0127 | 12.070 | ± | 0.484 | 11.593 | ± | 0.530 | 0.0834 | |
Nb. Ripple per min | 26.400 | ± | 1.400 | 24.833 | ± | 3.270 | 0.6921 | 56.000 | ± | 2.280 | 58.833 | ± | 2.982 | 0.4846 | |
Mean Inter-Ripple Interval (s) | 2.198 | ± | 0.122 | 2.646 | ± | 0.407 | 0.3580 | 1.071 | ± | 0.046 | 1.036 | ± | 0.050 | 0.6187 | |
Mean ripple duration (ms) | 99.373 | ± | 1.469 | 89.267 | ± | 2.155 | 0.0049 | 92.231 | ± | 5.169 | 73.079 | ± | 4.517 | 0.0206 | |
Peak PSD frequency (Hz) | 143.573 | ± | 4.228 | 150.758 | ± | 2.238 | 0.1919 | ||||||||
Ripple amplitude (nSD) | 1.795 | ± | 0.053 | 2.041 | ± | 0.042 | 0.0067 | ||||||||
Nb. spikes within ripples | 38.598 ± 5.077 27.096 ± 5.264 | 0.1549 | 35.980 ± 5.761 | 24.185 ± 5.225 | 0.1634 |