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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: CA Cancer J Clin. 2017 Dec 1;68(2):116–132. doi: 10.3322/caac.21438

Table I.

Staging Hodgkin lymphoma and risk factors

Stage Involved sites A or B suffix to stage
Limited stage favorable Limited stage unfavorable
I One node or a group of adjacent nodes Limited stage with additional risk factors *
  • >3-4 lymph node areas

  • Elevated ESR

  • Advanced age

  • ≥1 Extranodal sites

  • B symptoms

Absence or presence of B symptoms (below) qualifies any stage as A or B respectively
  1. Fevers. Unexplained fever with temperature above 38°C

  2. Night sweats. Drenching sweats

  3. Weight loss. Unexplained weight loss of more than 10% of the usual body weight in the 6 months prior to diagnosis

II Two or more nodal groups on the same side of the diaphragm
Advanced stage
II bulky Single nodal mass, in contrast to multiple smaller nodes, of 10 cm or greater than a third of the transthoracic diameter at any level of thoracic vertebrae
III Nodes on both sides of the diaphragm; nodes above the diaphragm with spleen involvement
IV Additional noncontiguous extra lymphatic involvement (for e.g. lung, liver or skeletal metastases)
*

Risk factors are defined differently by various study groups