Gene expression of BMNC after 24h in conditioned media from disc cell / P. acnes co-cultures. Time points (3h, 24h) and condition (1:10, 1:100, LPS) relate to the conditioned media. a, b, c, d: relative gene expression of IL1, IL6, IL8, and CCL2, respectively. Significant differences to BMNCs cultured in conditioned media from disc cells alone are indicated: * p<0.05, ** p <0.01, *** p<0.001.