Scheme 11.
Regioselective ruthenium(0) catalyzed [4+2] cycloaddition of 3,4-benzannulated 1,5-diynes with α-ketols and general catalytic mechanism.a
aYields are of material isolated by silica gel chromatography. RuPhos = 2-dicyclohexylphosphino-2′,6′-diisopropoxybiphenyl.