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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Aliment Pharmacol Ther. 2018 Jan 29;47(7):1001–1011. doi: 10.1111/apt.14531

Table 6.

Known Groups Validity: Correlations between PRO scores and Number of Comorbidities

Measure Number of Comorbidities
Spearman’s correlationa (95% CI)
HIT-6 scoreb 0.31 [0.25, 0.37]
PROMISb
 Fatigue 0.39 [0.34, 0.44]
 Pain Interference 0.53 [0.48, 0.57]
 Sleep Disturbance 0.41 [0.36, 0.46]
 Depression 0.30 [0.24, 0.36]
 Cognitive Concerns 0.33 [0.27, 0.38]
 Anger 0.29 [0.23, 0.35]
 Anxiety 0.30 [0.24, 0.36]
 Belly Pain 0.34 [0.28, 0.40]
 Diarrhea 0.20 [0.14, 0.27]
 Nausea/Vomiting 0.29 [0.23, 0.35]
HCV-PROc −0.48 [−0.53, −0.43]

Note: CI=Confidence Interval; Sample size ranges from 887–961.

a

Spearman’s rank correlation coefficient (Rho)

b

Higher values of HIT-6 and PROMIS T-scores indicate more severe symptoms.

c

Higher values indicate higher functional well-being.