Table 1.

Ebola vaccination strategies.

Ebola vaccination strategies
Reactive:	Ring vaccination:
Emergency response vaccination following identification of an Ebola case or cases	Includes case contacts and contacts of contacts (identified through contact tracing). Community HCW/FLWs at-risk may also be included
	Ring vaccination modified with a geographic boundary:
	Includes case contacts and contacts of contacts (identified through contact tracing), and individuals residing within designated natural or man-made geographic boundaries where contact with the case(s) is judged likely. Community HCW/FLWs at-risk are may also be included
	Geographically targeted vaccination:
	Includes a population within a designated geographic boundary determined to be at risk of outbreak spread. Geographic boundary is determined based on outbreak characteristics and existing natural or man-made barriers that are likely to curtail population movement
	Mass vaccination:
	Includes a large population (district, subnational division, country, region) determined to be at risk of outbreak spread. Requires large vaccine supply and is unlikely to be feasible using an unlicensed vaccine under an investigational protocol
	HCW/FLW vaccination (reactive):
	Targeted reactive vaccination of HCW/FLWs in an outbreak limited to a health facility or set of health facilities
Preemptive:	HCW/FLW vaccination (preemptive):
Planned vaccination of a group of high-risk individuals before an outbreak occurs.	May include HCW/FLWs at a community, district, or national level in affected countries, international responders, and laboratory personnel
	Contacts of EVD survivors:
	Contacts of male survivors post-outbreak have the greatest risk of infection based on current evidence. Both female and male sexual and household contacts of survivors may be included pending additional evidence of viral persistence and transmission

Abbreviations: HCW/FLWs, healthcare and frontline workers; EVD, Ebolavirus disease.