Skip to main content
. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: J Biopharm Stat. 2017 Oct 30;28(2):292–308. doi: 10.1080/10543406.2017.1379532

Table 2.

Simulation results for EBSD and BSD for testing a single hypothesis (n = 500)

Test B1 B0 B δ θγ

BSD EBSD BSD EBSD BSD EBSD BSD EBSD BSD EBSD
quantitative interaction
π,πeopt
0.2 1 0.2 0 0.2 0.188 0.2 0.480 0.2 0.675
true 0.211 0.211 0.097 0.097 0.120 0.120 0.114 0.114 0.030 0.030
estimate 0.211 0.212 0.097 0.098 0.120 0.118 0.110 0.113 0.030 0.030
std.p 0.090 0.041 0.049 0.044 0.043 0.043 0.103 0.084 0.017 0.011
std.e 0.091 0.040 0.049 0.044 0.044 0.043 0.103 0.085 0.017 0.011
coverage 0.943 0.952 0.949 0.945 0.951 0.949 0.942 0.946 0.944 0.947

qualitative interaction
π,πeopt
0.2 1 0.2 0 0.2 0.214 0.2 0.521 0.2 0.710
true 0.171 0.171 −0.163 −0.163 −0.097 −0.097 0.334 0.334 0.044 0.044
estimate 0.171 0.171 −0.162 −0.164 −0.097 −0.096 0.335 0.333 0.044 0.044
std.p 0.097 0.044 0.045 0.040 0.042 0.041 0.107 0.084 0.018 0.011
std.e 0.100 0.044 0.045 0.041 0.042 0.041 0.108 0.085 0.018 0.011
coverage 0.944 0.948 0.951 0.941 0.949 0.945 0.947 0.948 0.941 0.951

γ = 0.1 is assumed for θγ. We also set π = 20%, α = 0.05, nsim = 1000