1.
Patient characteristics
| Characteristics | PNI-positive [n (%)] | P | PNI-negative [n (%)] | P | ||
| Derivation cohort | Validation cohort | Derivation cohort | Validation cohort | |||
| IQR, interquartile range; CEA, carcinoembryonic antigen; PNI, perineural invasion; P-value was derived from the comparison of patient characteristics between derivation cohort and validation cohort, within PNI-positive subgroup and PNI-negative subgroup respectively. | ||||||
| Age
[median (IQR)] (year) |
62 (50.0, 70.0) | 61 (51.5, 67.8) | 0.865 | 63 (54.0, 73.0) | 64 (53.0, 72.0) | 0.872 |
| Sex | 0.515 | 0.577 | ||||
| Male | 48 (73.8) | 23 (67.6) | 174 (61.9) | 118 (64.5) | ||
| Female | 17 (26.2) | 11 (32.4) | 107 (38.1) | 65 (35.5) | ||
| Tumor location | 0.555 | 0.030 | ||||
| Cecum-ascending colon | 20 (30.8) | 7 (20.6) | 49 (17.4) | 52 (28.4) | ||
| Transverse-descending colon | 5 (7.7) | 4 (11.8) | 20 (7.1) | 12 (6.6) | ||
| Sigmoid colon | 10 (15.4) | 8 (23.5) | 80 (28.5) | 38 (20.8) | ||
| Rectum | 30 (46.2) | 15 (44.1) | 132 (47.0) | 81 (44.3) | ||
| CEA level | 0.542 | 0.065 | ||||
| Normal | 29 (44.6) | 13 (38.2) | 188 (66.9) | 107 (58.5) | ||
| Abnormal | 36 (55.4) | 21 (61.8) | 93 (33.1) | 76 (41.5) | ||
| TNM staging | ||||||
| I | 1 (1.5) | 1 (2.9) | 0.307 | 57 (20.3) | 28 (15.3) | 0.186 |
| II | 9 (13.8) | 9 (26.5) | 103 (36.7) | 74 (40.4) | ||
| III | 43 (66.2) | 21 (61.8) | 93 (33.1) | 70 (38.3) | ||
| IV | 12 (18.5) | 3 (8.8) | 28 (10.0) | 11 (6.0) | ||