Fig. 2.

Association between sedentariness and CSF biomarkers. Participants were divided into lowest 25th (n = 21), middle 50th (n = 43), and highest 25th (n = 21) percentiles according to sedentariness levels; and mean Aβ42 (A), t-tau (B), p-tau (C), t-tau/Aβ42 (D), and p-tau/Aβ42 (E) levels of each group were plotted. Figures reflect values adjusted for age, sex, APOE ε4 status, the interval between CSF collection and accelerometer data, and assay batch. Abbreviations: CSF, cerebrospinal fluid; Aβ42, amyloid β 42; t-tau, total tau; p-tau, phosphorylated tau; a.u., arbitrary units; APOE ε4, apolipoprotein E ε4 allele.