2.
Correlation between preoperative F-NLR and clinical laboratory characteristics of patients with NSCLC
| Variables | F-NLR=0 (n=207) | F-NLR=1 (n=154) | F-NLR=2 (n=228) | P |
| F-NLR: combination of fibrinogen concentration and neutrophil to lymphocyte ratio; NLR: neutrophil to lymphocyte ratio; WBC: white blood cell; PLT: platelet count; ALP: alkaline phosphatase; Hb: hemoglobin; LDH: lactate dehydrogenase. | ||||
| Age, years | 59.3±9.4 | 62.6±9.5 | 60.0±9.3 | 0.001 |
| Maximum tumor diameter (cm) | 3.3±1.4 | 4.4±1.8 | 5.1±2.4 | <0.001 |
| NLR | 1.6±0.4 | 1.7±0.4 | 3.2±1.0 | <0.001 |
| Fibrinogen (g/L) | 2.8±0.4 | 4.3±0.6 | 4.1±1.0 | <0.001 |
| Neutrophil ratio (%) | 53.8±6.5 | 55.8±6.2 | 67.3±4.8 | <0.001 |
| Monocyte ratio (%) | 7.6±2.3 | 7.9±2.1 | 7.9±2.2 | 0.333 |
| Lymphocyte ratio (%) | 35.2±6.1 | 33.5±6.7 | 22.3±4.3 | <0.001 |
| D-dimer (mg/L) | 0.16±0.09 | 0.21±0.27 | 0.20±0.17 | 0.119 |
| WBC count (×103/μL) | 6.1±1.6 | 7.0±1.9 | 7.4±1.5 | <0.001 |
| PLT (×109/L) | 225.6±63.1 | 265.5±80.9 | 252.7±72.4 | <0.001 |
| ALP (U/L) | 70.4±23.4 | 77.5±22.7 | 78.0±31.6 | <0.001 |
| Hb (g/L) | 140.2±18.2 | 138.0±13.4 | 137.8±14.6 | 0.269 |
| LDH (U/L) | 178.3±53.6 | 180.3±47.8 | 185.4±55.4 | 0.284 |
| Survival period (months) | 51.3±22.7 | 44.7±24.4 | 37.6±25.6 | <0.001 |