Table 2.
Studies included in the meta-analysis
| Cell type | Markers of cell identity | Method | Cutoff | Reference |
|---|---|---|---|---|
| iPSC and iPSC-derived NSC | Nestin (NSC) | RNA-seq | FDR <0.05 | [42] |
| ESC and ESC-derived NSC | Nestin, PAX6, Ki67 (NSC) | Gene microarray | P < 0.001 | [76] |
| iPSC | Markers for pluripotency | Gene microarray | FDR <0.05 | [24] |
| iPSC-derived NSC and neurons | Nestin, PAX6 (NSC) TUBB3,MAP2A/B, DARPP-32, BCL11B (neurons differentiated towards striatal-like) | Gene microarray | absolute value of fold change >2 | [26] |
| iPSC-derived neurons | TUJ1, MAP2, GABA, GAD65, DARPP-32, Calbindin (neurons differentiated towards GABAergic striatal like) | Gene microarray | Adjusted P < 0.05 and fold change >1 | [33] |
| iPSC-derived neurons | TUBB3, DARPP-32, GAT1 (neurons differentiated towards GABAergic MS-like) | Gene microarray | P < 0.05 | [25] |
| ESC and ESC-derived neurons | MAP2, GABA, GAD65 (neurons differentiated towards GABAergic-like) | IPG-IEF and LC-MS/MS | P < 0.05 | [34] |
| iPSC and iPSC-derived neurons | MAP2 (neurons) | Western blot, 2D electrophoresis and LC-MS/MS | P < 0.05 | [47] |