Table 1.
The clinical characteristics of subjects
| Never-smoker (n = 17) | Smoker (n = 25) | |
|---|---|---|
| Male/female | 8/9 | 11/14 |
| Age | 56.2 ± 7.3 | 56.2 ± 5.7 |
| BMI | 26.4 ± 5.5 | 25.2 ± 2.9 |
| Pack years | 0 | 38.1 ± 13.5 |
| Cig/day during past 6 months | 0 | 17.1 ± 6.3 |
| FEV1 [%] post-bronchodilator | 118 ± 15.8 | 107 ± 12.8* |
| FEV1/FVC [%] post-bronchodilator | 80.5 ± 6.4 | 77.7 ± 5.1 |
| BAL macrophages [%] | 90.2 ± 3.8 | 95.9 ± 2.4*** |
| BAL lymphocytes [%]a | 6.6(3, 15.4) | 2(1,7.4) |
| BAL neutrophils [%]a | 1.3 (0.6, 4.4) | 0.6(0, 3.6)* |
| BAL eosinophils [%]a | 0(0, 0.6) | 0(0, 1.4) |
| BAL basophils [%]a | 0(0, 0) | 0(0, 0.4) |
| BAL mast cells [per 10 visual fields] | 2(0, 5) | 3(0, 13) |
Data is expressed as mean ± standard deviation and tested by using t-test.a, skew data, presented as median(range) and tested by Mann-Whitney U test; *, p < 0.05; ***, p < 0.001, compared with Never-smokers