Fig. 3.

Significant loss of fibre density, cross-section and fibre density and cross-section in the visual pathways of patients with a history of optic neuritis. To enable visualisation, streamlines from the template-derived whole-brain tractography map were cropped to include streamlines that correspond with significant fixels (family-wise error corrected p-value < 0.05), and coloured by p-value. Significant tracts are overlayed on a 2D glass-brain in the axial, coronal and sagittal plane. A close-up of the significant fixels are displayed in the lowest panel. Results are displayed on the population-specific template. FD = fibre density, FC = fibre cross-section, FDC = fibre density and cross-section.