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. 2018 Mar 7;18:264. doi: 10.1186/s12885-018-4050-1

Fig. 15.

Fig. 15

Back-to-front pattern of binding. a) Depiction of the presence of Hit in the active site pocket in back-to-front fashion. A clear enlarged cavity is represented in b and c. The ligand was found to be seated firmly with Cys919 from the top and is sandwiched with Glu885 and Asp1046