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. 2018 Mar 7;8:19. doi: 10.1186/s13578-018-0216-4

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effect of RSV in mMSCs stimulated with PMMA particles. a KCNQ1OT1 relative expression levels and the mRNA and protein expression levels of β-catenin in mMSCs stimulated with PMMA particles treated with or without RSV at different concentration. b ALP activity in mMSCs stimulated with PMMA particles treated with or without RSV at different concentration. c The mRNA expression levels of Runx2, Osterix and OCN in mMSCs stimulated with PMMA particles treated with or without RSV at different concentration. d Osteoblastic differentiation in mMSCs stimulated with PMMA particles treated with or without RSV at different concentration assessed by ARS staining. *P < 0.05 compared with control group. ^&P < 0.05 compared with PMMA group