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. 2018 Mar 7;16:51. doi: 10.1186/s12967-018-1426-6

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effects of long-term treatment with rIL-18 on the kidney. Histopathological analysis was conducted to assess renal damage with rIL-18 exposure for 12 weeks. a Hematoxylin–eosin, b periodic acid–Schiff, c periodic acid methenamine silver, and d azan staining. Scale bars represent 50 μm (a–d)