Table 2.
Genotype ADRB1 | TCM | Controls with CAD | Controls w/o CAD |
---|---|---|---|
(n = 248) | (n = 156) | (n = 223) | |
CC | 138 (55.6%) | 90 (57.7%) | 128 (57.4%) |
CG | 93 (37.5%) | 53 (34%) | 79 (35.4%) |
GG | 17 (6.9%) | 13 (8.3%) | 16 (7.2%) |
Genotype GRK5 | TCM | Controls with CAD | Controls w/o CAD |
(n = 256) | (n = 160) | (n = 233) | |
AA | 253 (98.8%) | 155 (96.9%) | 227 (97.4%) |
AT | 3 (1.2%) | 5 (3.1%) | 6 (2.6%) |
TT | 0 (0%) | 0 (0%) | 0 (0%) |
Genotype BAG3 | TCM | Controls with CAD | Controls w/o CAD |
(n = 244) | (n = 159) | (n = 226) | |
CC | 28 (11.5%) | 14 (8.8%) | 14 (8.8%) |
GC | 118 (48.4%) | 78 (49.1%) | 99 (43.8%) |
GG | 98 (40.2%) | 67 (42.1%) | 95 (42%) |
Abbreviations: TCM Takotsubo cardiomyopathy; CAD coronary artery disease; ADRB1 = β1-adrenergic receptor; GRK5 G-protein-coupled receptor kinase 5; BAG3 Bcl-associated athanogene 3